Detalhe da pesquisa
1.
A Phase 1 study of the long-acting anti-IL-5 monoclonal antibody GSK3511294 in patients with asthma.
Br J Clin Pharmacol
; 88(2): 702-712, 2022 02.
Artigo
Inglês
| MEDLINE | ID: mdl-34292606
2.
Assessing efficacy in important subgroups in confirmatory trials: An example using Bayesian dynamic borrowing.
Pharm Stat
; 20(3): 551-562, 2021 05.
Artigo
Inglês
| MEDLINE | ID: mdl-33475231
3.
Efficacy and safety of mepolizumab administered subcutaneously for moderate to severe atopic dermatitis.
Allergy
; 75(4): 950-953, 2020 04.
Artigo
Inglês
| MEDLINE | ID: mdl-31515809
4.
Characterization of the relationship between dose and blood eosinophil response following subcutaneous administration of mepolizumab.
Int J Clin Pharmacol Ther
; 53(12): 1015-27, 2015 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-26445140
5.
Efficacy and safety of an anti-IL-13 mAb in patients with severe asthma: a randomized trial.
J Allergy Clin Immunol
; 133(4): 989-96, 2014 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-24582316
6.
The Pharmacokinetics and Relative Bioavailability of Mepolizumab 100 mg Liquid Formulation Administered Subcutaneously to Healthy Participants: A Randomized Trial.
Clin Pharmacol Drug Dev
; 9(3): 375-385, 2020 04.
Artigo
Inglês
| MEDLINE | ID: mdl-31317668
7.
Justification of the Subcutaneous Mepolizumab Dose of 300 mg in Eosinophilic Granulomatosis With Polyangiitis and Hypereosinophilic Syndrome.
Clin Ther
; 43(7): 1278-1280, 2021 07.
Artigo
Inglês
| MEDLINE | ID: mdl-34187697
8.
Safety, tolerability, pharmacokinetics and pharmacodynamics of single and repeat inhaled doses of umeclidinium in healthy subjects: two randomized studies.
Clin Drug Investig
; 33(7): 477-88, 2013 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-23784369
9.
Initial assessment of single and repeat doses of inhaled umeclidinium in patients with chronic obstructive pulmonary disease: two randomised studies.
Eur J Pharmacol
; 701(1-3): 40-8, 2013 Feb 15.
Artigo
Inglês
| MEDLINE | ID: mdl-23276660
10.
Quinidine does not affect the renal clearance of moxonidine.
Br J Clin Pharmacol
; 54(3): 251-4, 2002 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-12236844
11.
Metabolism and disposition of the antihypertensive agent moxonidine in humans.
Drug Metab Dispos
; 31(3): 334-42, 2003 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-12584161